Since 2003, the Department of Family and Community Medicine has been on the national list of top 20 Departments of Family Medicine in NIH funding. DFMC faculty members are on the forefront of trans-disciplinary research across several domains. The faculty has formed collaborations within the College of Medicine, across the University of Arizona, with other academic institutions nationally and internationally, with state and local health departments and community agencies, and communities of healthcare practitioners, educators, patients, and communities of color.

DFCM faculty researchers are leaders in:  tobacco cessation and prevention; obesity; diabetes; aging; methamphetamine and heroin use; epigenetics and substance use;  community and participatory research; mobile technologies; working with at-risk populations such as those with serious mental illness, developmental disabilities, and Native Americans and Mexican Americans. These research directions are being addressed at multiple levels, including community and clinical settings. DFCM researchers have begun to focus on the development of departmental capacity to use administrative and electronic health records data to evaluate ongoing care patterns and the impact of new programs within the COM practice and statewide AHCCCS (Medicaid) health care systems, and to implement clinical decision support systems for performance improvement.