• Education
• Outreach
• Research
• Patient Care
• People

Mikel Aickin, PhD

NIH/NCCAM R01 9/05-8/07
Methods Development for Early Phase CAM Trials
Early-phase CAM research is at a disadvantage for several reasons having to do with the inappropriate application of Phase III methods in Phase I trials. This project will conduct statistical and literature-based research on four of these areas of methodology (1) design-adaptive allocation in place of randomization, (2) paired availability to deal with missing data, (3) the benefits of replacing null hypothesis testing with separation tests, and (4) development of a clinic-based version of RCTs, using modern causal analysis.
Role: Principal Investigator

NIH/NHLBI R01 (Vogt) 9/04-6/08
Work, Weight, and Wellness: The 3W Program
This project is a comprehensive lifestyle change program delivered through worksites in partnership with a large health care system. The goal is to increase physical activity, improve diet, improve decision making about risk-reducing behaviors, and reduce obesity of hotel employees in Hawai'i.
Role: Investigator

NIH/NCCAM RO1 (Karanja) 09/04-06/09
INSIGHT: Metabolic Consequences of High and Low Carbohydrate Diets
This study will assess the short and long-term effects of two diets differing in macronutrient content on their effect on weight loss and weight loss maintenance. The study will also assess the effects of the diets on risk factors for chronic disease.
Role: Investigator

NIH/NCCAM R21 (Bell) 02/15/05-02/14/08
Polysomnography in Homeopathic Remedy Effects
This exploratory 3-year grant will examine the interaction of the remedy effects (Nux Vomica 30c and Coffea Cruda 30c) with two different human personality traits associated with insomnia (Type A hostility and panic-prone anxiety sensitivity) and overlapping those of persons reported in classical homeopathy to respond most strongly to each remedy. Primary dependent measures will derive from all-night polysomnographic EEG recordings in subjects' homes on four different pairs of nights over a 4-week period (including baseline, placebo, and remedy double-blind).
Role: Investigator

NIH/NICHD R21 (Ritenbaugh) 08/05-07/07
CHOICES: Family Physicians Treat Overweight Children
This project develops and pilot tests a group office visit model for treating overweight, predominantly Hispanic children, and their parents, in a 12-session intervention program.
Role: Investigator

NIH/NCCAM U01 (Ritenbaugh) 08/05-07/09
TCM for TMD: A Multi-site Whole Systems Trial
This project tests whole system Traditional Chinese Medicine (including acupuncture, herbs, tuina) for the treatment of temporomandibular dysfunction in a stepped-care approach in comparison with a validated psychosocial intervention. The Phase II trial has a unique design to provide guidance on the best combination of psychosocial care with TCM to evaluate in the Phase III trial.
Role: Investigator

NIH/NHLBI U01 (Karanja) 9/05-07/10
Primordial Prevention of Overweight in AI Children (PTOTS)
We propose a community-partnered randomized study to prevent early childhood overweight in American Indian (AI) children. A birth cohort of about 780 children from six Indian communities born over a period 18 months will be randomized by community to either a control (3 communities) or intervention condition (3 communities).
Role: Investigator

NIH/NHLBI R21 (Ritenbaugh) 04/06-03/08
Preventing CVD in Native Populations: The Traditional Living Challenge.
This project, designed and implemented in full partnership with Salish Kootenai College, will develop and test a traditional lifestyle experience to enhance behavioral change with regard to cardiovascular disease risk factors.
Role: Investigator

NIH/NCCAM K24 (Bell) 09/05 - 09/10
Individual Differences in CAM Patient-Centered Outcomes: Research & Mentorship
Project to mentor new CAM researchers, with emphasis on patient-centered outcomes.
Role: Investigator

NIH/NCCAM U01 (Haas) 9/1/06 - 8/31/11
Dose-Response/Efficacy of Manipulation for Chronic LBP
The goals are to determine the effect of the number of treatments for spinal manipulation on clinical outcomes for chronic LBP sufferers, and determine the cost-effectiveness of the number of treatments.
Role: Investigator

NIH/NIDDK R34 (Bassford) 04/01/06 - 03/31/09
Group Visits for Treating Type 2 Diabetes in Hispanics
This planning grant will pilot test a group office visit model for the clinical care of type 2 diabetes, and plan for a multi-clinic randomized trial.
Role: Investigator