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Iris Bell, MD, PhD

NIH/NCCAM R21 02/15/05-02/14/08
Polysomnography in Homeopathic Remedy Effects
This exploratory 3-year grant will examine the interaction of the remedy effects (Nux Vomica 30c and Coffea Cruda 30c) with two different human personality traits associated with insomnia (Type A hostility and panic-prone anxiety sensitivity) and overlapping those of persons reported in classical homeopathy to respond most strongly to each remedy. This study will contribute to our long-range goal of understanding the neurophysiological and biopsychosocial mechanisms of classical homeopathic remedy treatment in patients with specific clinical conditions.
Role: Principal Investigator

NIH/NCCAM K24 10/01/05-09/29/10
Research on Complementary and Alternative Medicine
This K24 NIH award renewal is intended to develop Dr. Bell as a mentor for junior investigators in CAM research and to develop her physiological research using complex nonlinear dynamical systems approaches to understanding processes and mechanisms of whole systems of CAM such as homeopathy.
Role: Principal Investigator

NIH/NCCAM T32 8/1/02-7/31/07
Arizona CAM Research Training Program Grant
This is a 5-year T32 proposal to establish a rigorous predoctoral and postdoctoral interdisciplinary educational program for investigators preparing for a career in CAM and integrative medicine (IM) research.
Role: Principal Investigator

NCCAM R21 7/1/06-6/30/09
Dilution and Succussion in Homeopathic Remedy Dose-Response Patterns
This 3-year exploratory study will evaluate the usefulness of quantitative EEG responses to olfactory administration of two different homeopathic remedies (Pulsatilla and Sulphur) prepared with different amounts of dilution and succussion, toward developing an objective biomarker for active homeopathic remedies.
Role: Principal Investigator

NCCAM R01 (Ritenbaugh) 07/01/2006-06/30/2009
Developing Patient-Centered Measures for Outcomes of CAM Therapies
This project will undertake secondary data analysis on qualitative interviews from CAM studies to identify natural language in regard to non-specific "transformative" outcomes, develop these into questionnaires, and fully evaluate the questionnaires in a multi-ethnic approach.
Role: Investigator

NCCAM R01 (Aickin, Ph.D) 9/05-8/07
Methods Development for Early Phase CAM Trials
Early-phase CAM research is at a disadvantage for several reasons having to do with the inappropriate application of Phase III methods in Phase I trials. This project will conduct statistical and literature-based research on four of these areas of methodology (1) design-adaptive allocation in place of randomization, (2) paired availability to deal with missing data, (3) the benefits of replacing null hypothesis testing with separation tests, and (4) development of a clinic-based version of RCTs, using modern causal analysis.
Role: Investigator